Located in Valdebebas, Hotel101 Madrid sits opposite the neighbourhood's railway station and close to Adolfo Suárez Madrid-Barajas Airport, IFEMA, Real Madrid City, and the MADRING Formula 1 circuit. Although outside Madrid's historic centre, its transport connections make the property particularly practical for flights, exhibitions, sporting events, and business travel.

Opened on 10 March 2026, the property marked Hotel101's first European opening. Its concept centres on a technology-supported, standardised hospitality model, with a consistent room format and contemporary shared spaces designed to serve short stays, business visits, families, and event-driven travel.

The hotel contains 680 HappyRooms across nine storeys, placing it among Spain's largest hotels by room count. Every room follows the brand's uniform design approach and includes air conditioning, a private bathroom, complimentary WiFi, and a kitchenette equipped with a microwave, providing additional flexibility for longer stays and airport stopovers.

Beyond the rooms, the property offers seasonal outdoor swimming pools, a children's pool, a full-size gym, business and function spaces, a convenience store, laundry facilities, and more than 200 parking spaces. HBNB Kitchen by La Sucursal brings a locally operated Mediterranean dining concept to the hotel, supported by a café and poolside drinks during the warmer months.

Hotel101 Madrid is best suited to airport stopovers, IFEMA visitors, business travellers, families, sports audiences, and guests attending major events in Valdebebas. Its scale and standardised room concept favour convenience and consistency over the intimate atmosphere of a traditional boutique property.